Guidelines for Selection of the Emulsifiers of Pharmaceutical Purposes
Category: Technical Documents
Date: 2024-05-08
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Author: JZ
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In the pharmaceutical industry,emulsifiers as one of the key production equipment, are crucial for the preparation of high-quality emulsion medicines.The emulsification process involves  the uniform dispersion of two insoluble liquids (usually oil and water phases) to form a stable emulsion,a process that has a direct impact on the quality,stability and bioavailability of the final product.Therefore the correct selection of emulsifying machine is the basis for ensuring production efficiency and product quality.With more than 20 years of experience in emulsifying machine production and design,Jinzong provides you with a detailed guide to help you make an informed decision among many options. 

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1、Indentify Production Requirements

       

Emulsion Types:It is first necessary to determine whether the emulsion to be produced is O/W or W/O,and different emulsion types may need different emulsifer designs.


Production Scale:According to the actual production needs to choose the appropriate capacity of the emulsifying machine,such as 200L double-cylinder hydraulic lift vacuum homogenizing emulsifying machine is suitable for a certain scale of production. 

  

2、Characteristic of Material

  

Physical & Chemical Properties:Considering the viscosity, density, surface tension and other characteristics of the material,these factors will affect the emulsification effect and the suitability of the equipment.


Stability Requirements:Select the equipment that can provide the appropriate shear force and mixing strength according to the stability and sensitivity of the medicine.


3、Emulsifying Machine Performance:

  

Shear Force and Homogenizing Effect:Select equipment with efficient shearing and homogenizing capabilities,such as high shear homogenizing emulsifiers,to ensure uniform emulsion particle size distribution and improve product quality.

  

Mixing System:Concidering the fixed rotor design,choose the shear head configuration that provides the best mixing results,balancing energy consumption and mixing efficiency.


Lift and Vacuum Function:If you need to handle Heat-Sensitive or easily oxidized materials,choose an emulsifier with a hydraulic lift and vacuum system to help reduce oxidation and improve the gentleness of material handling.

 

4、Operation and Maintanance:


Cleaning and Sterilization:Consider the cleaning convenience of the equipment and whether it is easy to CIP or SIP.


Safety and Compliance:Ensuring equipment complies with GMP standards,easy verification and documentation to meet the stringent regulatory requirements of the pharmaceutical industry.

5、Technology Support and Service:


Supplier Selection:Working with suppliers with rich industry expereience and technical support capabilities,they can provide comprehensive solutions from equipment selection to after-sales maintenance.

  

Customized Service:According to the specific production process requirements,considering whether a  custom emulsifier design is required.


Conclusion

  

Choosing an emulsifier for pharmaceutical use is a complex process that involves many considerations and requires careful analysis and balance.By belowing the above guidlines,combining their specific needs,and working closely with experienced suppliers,you can  more accurately select the most suitable emulsifier,laying a solid foundation for medicine production.In the constantly changing pharmaceutical  field,constinuous technogical innovation and service support are also important factors that cannot be ignored when choosing partner.

  

For more than 20 years, Jinzong has focused on the design and manufacturing of food and pharmaceutical,design and manufacturing of cosmetic machinery and equipment,intelligent control system reserach and development,engineering design and installation,etc.It has a design and marketing service center in Guangzhou, and 2 production plants in Zhaoqing National High-tech Zone. It has special equipment pressure vessel manufacturing qualification and pressure pipeline installation (GC2) qualification. It is a national high-tech enterprise and a provincial specialized and special new enterprise, with 2 provincial famous products, dozens of product patents, software copyrights and provincial high-tech products. Through the national intellectual property standard certification, ISO9001-2015 international quality system certification and EU CE certification, it has been rated as "Guangdong Province's contract-abiding and creditworthy Enterprise" by Guangdong Provincial Bureau of Industry and Commerce for many years, with users in more than 50 countries and areas around the world, and has been widely recognized and supported by more than 2,000 large and small enterprises at home and abroad.

  

"If a worker wants to do a good job, he must first sharpen his tools", Jinzong enterprise adheres to the concept of " Quality is like Gold, Craftsmanship is Purpose", and provides advanced and automated production lines to the manufacturing factories. Welcome friends at home and abroad to visit and guide!


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